| Athlete | 2025 | 2024 | Difference |
| London Cox - Decatur High School | 5:28.85 | 6:24.21 | -55.36 |
| Kate Sanders - Athens High School | 5:31.14 | 6:21.59 | -50.45 |
| Livia Dwyer - Montgomery Academy | 5:25.35 | 6:07.11 | -41.76 |
| Leah Anderson - Hewitt-Trussville HS | 5:36.89 | 6:16.07 | -39.18 |
| Elizabeth Harris - Shades Valley High School/JCIB | 5:54.33 | 6:33.03 | -38.7 |
| De'Nya Reynolds - Cornerstone Schools of Alabama | 5:30.72 | 6:08.93 | -38.21 |
| Bristol Fleenor - Northridge High School | 5:34.03 | 6:11.46 | -37.43 |
| Cadence Rivera - Haleyville High School | 5:34.92 | 6:07.38 | -32.46 |
| Paizley Whitlow - Cold Springs | 5:41.77 | 6:13.45 | -31.68 |
| Riley Zeanah - Vestavia Hills HS | 4:59.02 | 5:29.93 | -30.91 |
| Molly Halter - Bob Jones | 5:17.29 | 5:47.22 | -29.93 |
| Hannah Quick - Chelsea High School | 5:24.24 | 5:52.91 | -28.67 |
| Laila Cooper - Robertsdale | 5:32.87 | 6:01.21 | -28.34 |
| Emily Wester - Pelham | 5:07.17 | 5:34.34 | -27.17 |
| Mary Taylor - Whitesburg Christian Academy | 5:31.62 | 5:58.22 | -26.6 |
| Ellie Gehri - Oneonta | 5:31.43 | 5:57.05 | -25.62 |
| Meredith Walker - Randolph School | 5:47.26 | 6:12.17 | -24.91 |
| Aimee von Herrmann - Florence High School | 5:16.97 | 5:41.42 | -24.45 |
| Mariah Ruff - Fairhope | 5:40.30 | 6:03.97 | -23.67 |
| Lindley Kate Boulware - Northridge High School | 5:52.62 | 6:15.91 | -23.29 |
| Aileen Mulligan - Saint James | 5:51.63 | 6:12.83 | -21.2 |
| Banks Bradford - Scottsboro HS | 4:58.89 | 5:19.93 | -21.04 |
| Morgan Parks - Smiths Station | 5:47.93 | 6:08.44 | -20.51 |
| Abbie Dickeson - White Plains | 5:32.48 | 5:52.90 | -20.42 |
| Claire Spooner - Vestavia Hills HS | 5:07.57 | 5:27.91 | -20.34 |
| Ava Sparks - Hoover | 5:00.42 | 5:20.63 | -20.21 |
| Isabelle Allan - Whitesburg Christian Academy | 5:21.10 | 5:40.99 | -19.89 |
| Ava Fields - Oak Mountain HS | 4:57.31 | 5:16.52 | -19.21 |
| Hadley Turner - Hewitt-Trussville HS | 5:08.26 | 5:27.20 | -18.94 |
| Reese Dupuis - Huntsville HS | 5:14.12 | 5:32.05 | -17.93 |
| Kassidy Young - Grissom HS | 5:28.32 | 5:46.05 | -17.73 |
| Caroline Newby - Huntsville HS | 5:52.69 | 6:10.33 | -17.64 |
| Francesca Demarco - Mountain Brook HS | 5:25.32 | 5:42.30 | -16.98 |
| Millie Black - Vestavia Hills HS | 5:26.24 | 5:43.21 | -16.97 |
| Taylor Larson - Buckhorn | 5:40.97 | 5:57.40 | -16.43 |
| Lena Anne Parker - Briarwood Christian School | 5:30.81 | 5:47.06 | -16.25 |
| Teresa Ye - Saraland High School | 5:32.20 | 5:48.31 | -16.11 |
| Hannah Jacobs - Providence Christian School | 5:48.54 | 6:04.25 | -15.71 |
| Reese Avenel - Scottsboro HS | 5:35.33 | 5:50.04 | -14.71 |
| Kaylie Key - Athens Bible School | 5:25.44 | 5:40.03 | -14.59 |
| Sarah Hertz - Hoover | 5:03.81 | 5:18.27 | -14.46 |
| Amelia Scales - Huntsville HS | 5:19.82 | 5:34.00 | -14.18 |
| Haley Dumas - Lawrence County HS | 5:47.62 | 6:01.44 | -13.82 |
| Olivia Kahn - Lee-Scott Academy | 5:42.79 | 5:56.51 | -13.72 |
| Anna Ragsdale - Randolph School | 5:33.01 | 5:45.52 | -12.51 |
| Scarlett Odvody - Fairhope | 5:50.85 | 6:03.15 | -12.3 |
| Natalie Wiram - Hewitt-Trussville HS | 5:27.04 | 5:38.58 | -11.54 |
| Gabrielle Jeffery - Huntsville HS | 5:11.26 | 5:22.15 | -10.89 |
| Catarina Williams - Oak Mountain HS | 5:06.51 | 5:17.22 | -10.71 |
| Anna Erdberg - Mountain Brook HS | 5:06.75 | 5:17.36 | -10.61 |
| Addie Bazemore - Mountain Brook HS | 5:38.53 | 5:49.14 | -10.61 |
| Lynley Grace Anderson - Fairhope | 5:47.75 | 5:58.22 | -10.47 |
| Addison Joose - Scottsboro HS | 5:51.42 | 6:01.75 | -10.33 |
| Yeira Guzman - Brewer | 5:44.37 | 5:54.60 | -10.23 |
| Ree Sasser - Spanish Fort | 5:32.98 | 5:43.11 | -10.13 |
| Rachael Matthews - Hazel Green | 5:50.35 | 6:00.34 | -9.99 |
| Madeline Rooks - Vestavia Hills HS | 5:47.47 | 5:57.43 | -9.96 |
| Sasha Crowe - Saint John Paul II Catholic High School | 5:33.58 | 5:43.51 | -9.93 |
| Sarah Adams - Westminster School at Oak Mountain | 5:48.85 | 5:58.54 | -9.69 |
| Annie Midyett - Bayside Academy | 5:10.62 | 5:20.28 | -9.66 |
| Bailey Unger - Fayette County High School | 5:46.06 | 5:55.58 | -9.52 |
| Lily Hatton - Brooks | 5:42.58 | 5:51.75 | -9.17 |
| Caroline Couey - Opelika High School | 5:06.74 | 5:15.87 | -9.13 |
| Mary Durham - Hewitt-Trussville HS | 5:07.17 | 5:16.12 | -8.95 |
| Madison Harvey - Spain Park | 5:23.26 | 5:32.10 | -8.84 |
| Gabriela Vega - Fort Payne | 5:46.11 | 5:54.50 | -8.39 |
| Cambree Bradford - Scottsboro HS | 5:26.64 | 5:34.94 | -8.3 |
| Lillie Meeks - Whitesburg Christian Academy | 5:17.78 | 5:25.54 | -7.76 |
| Katelin Stiefel - Sand Rock | 5:54.91 | 6:02.40 | -7.49 |
| Bailey Zinn - Homewood HS | 5:23.51 | 5:30.95 | -7.44 |
| Katelyn Patton - Northside | 5:33.54 | 5:40.97 | -7.43 |
| Mary Spann - Altamont | 5:40.24 | 5:47.65 | -7.41 |
| Haleigh Rowe - Huntsville HS | 5:21.15 | 5:28.28 | -7.13 |
| Hayley Datema - Oak Mountain HS | 5:23.75 | 5:30.84 | -7.09 |
| Janelle Ramos - Pelham | 5:16.66 | 5:23.72 | -7.06 |
| Allie Hale - Briarwood Christian School | 5:21.29 | 5:27.79 | -6.5 |
| Juliann Reid - Saint John Paul II Catholic High School | 5:40.84 | 5:47.01 | -6.17 |
| Hanna Sheffield - Thompson | 5:31.38 | 5:37.42 | -6.04 |
| Ava Kelly - Saraland High School | 5:38.28 | 5:44.13 | -5.85 |
| Georgia Jayne Stuckey - Mountain Brook HS | 5:12.44 | 5:17.76 | -5.32 |
| Kaitlyn Bybee - Straughn High School | 5:50.16 | 5:55.46 | -5.3 |
| Ami Marks - Bob Jones | 5:29.39 | 5:34.67 | -5.28 |
| Sarah Tole - Auburn | 4:57.80 | 5:03.03 | -5.23 |
| Marin McWilliams - Homewood HS | 5:40.88 | 5:46.07 | -5.19 |
| Rose Betts - Brewer | 5:01.79 | 5:06.94 | -5.15 |
| Amelia Wilbourn - Huntsville HS | 5:28.11 | 5:32.91 | -4.8 |
| Josie Kemper - Fairhope | 5:42.89 | 5:47.56 | -4.67 |
| Kaitlyn Smith - Smiths Station | 5:31.94 | 5:36.04 | -4.1 |
| Catherine Wallace - Hoover | 5:05.52 | 5:09.57 | -4.05 |
| Hannah Porr - McGill-Toolen Catholic | 5:43.18 | 5:47.13 | -3.95 |
| Emerson Maniscalco - Oxford High School (AL) | 5:48.36 | 5:51.64 | -3.28 |
| Joy McBride - DAR | 5:34.35 | 5:37.55 | -3.2 |
| Kyndal Hughes - Fort Payne | 5:21.51 | 5:24.52 | -3.01 |
| Natalie Schoonover - Auburn | 5:38.43 | 5:41.27 | -2.84 |
| Mary Grace Parker - Briarwood Christian School | 5:00.51 | 5:03.18 | -2.67 |
| Zarya Jackson - Pinson Valley High School | 5:26.85 | 5:29.49 | -2.64 |
| Kenly Cooper - UMS-Wright | 5:30.80 | 5:33.41 | -2.61 |
| Leah Sitterson - Huntsville HS | 5:28.40 | 5:30.99 | -2.59 |
| Valeria Escalera - Auburn | 5:32.81 | 5:35.26 | -2.45 |
| Maggie Shaw Cox - Auburn | 5:46.54 | 5:48.87 | -2.33 |
| Faith Scardino - Oak Mountain HS | 5:25.17 | 5:27.23 | -2.06 |
| Kennedy Hamilton - Mountain Brook HS | 4:59.66 | 5:00.97 | -1.31 |
| Jessa Nash - Central - Clay County | 5:51.39 | 5:52.64 | -1.25 |
| Khloe Nalley - Cullman | 5:31.47 | 5:32.51 | -1.04 |
| Emma Brooke Levering - Homewood HS | 4:58.44 | 4:59.19 | -0.75 |